肿瘤热治疗系统的模糊逻辑PID 控制器设计
宋明扬，蔡张浩，白景峰，孙建奇，徐学敏
（上海交通大学生物医学工程学院，Med-X 研究院，上海 200030）
摘要：本文介绍了一个冷热疗系统，它可以将冷热交替治疗的优点应用于肿瘤治疗中。同时，我们为该冷热交替治疗系统设计了新颖的控制系统，以保证其有效工作。首先，热疗时，该控制系统可以保证射频探针周围的组织温度保持在一个合理的范围之内。其次，设计的模糊逻辑PID 控制器可以保证热疗时实现温度的精确控制。在离体猪肝上所做的实验结果表明，所提出控制方法让该冷热治疗系统具备良好的性能。
关键词：模糊逻辑PID 控制器；冷热疗系统；探针防过热保护
中图分类号：TP273

The design of thermal treatment system via fuzzy logic PID
Song Mingyang, Cai Zhanghao, Bai Jingfeng, Sun Jianqi, Xu X. Lisa
(School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University,ShangHai 200030)
Foundations: National Natural Science Foundation of China (NSFC11005074, NSFC50725622); Specialized Research Fund for the Doctoral Program of Higher Education (20100073120004); Biomedical Engineering Cross-Research Fund of Shanghai Jiaotong University (No. YG2010MS81)
Brief author introduction:Song Mingyang, Male, Master Candidate, Intelligent Control of Medical Instruments.
Correspondance author: Jianqi Sun, (1981-), Male, Assistant Research Professor,Synchrotron Radiation Imaging and Medical Device.
Abstract: In this paper, a cryosurgery-hyperthermia system is proposed for taking advantage of the alternated cooling and heating treatment in tumor. A novel control system is proposed to ensure that the thermal system works effectively. First, the tissue temperature around the probe is regulated and kept in a desired range when radio frequency ablation is operated. Sectumor sizeond, precise control of temperature is achieved in hyperthermia treatment using fuzzy logic PID type controller. The results of ex vivo liver experiment demonstrate that this system could provide a rather good performance with the proposed control method.
Keywords: fuzzy logic PID; cryosurgery-hyperthermia system; protecting probe from overheat