快速止血的机遇和挑战
岳媛媛1，龚剑萍2，徐晓帆1，李萌萌1，罗忠礼1
基金项目：本项目研究获得了“高等学校博士学科点专项科研基金新教师类资助课题”其项目编号为(20115503120010)支持；国家自然科学基金（NSFC）编号（81101417）支持
作者简介：岳媛媛（1989－），女，硕士研究生，主要从事临床检验，创伤修复，组织及器官再生
通信联系人：罗忠礼（1976－），男，博士，副教授，主要从事基础医学，纳米生物医学，创伤修复，组织及器官再生工程等.

（1. 重庆医科大学基础医学院；2. 重庆医科大学第一临床学院）
摘要：创伤伴随着出血和止血过程，正常止血机理对于人体大面积受伤出血若不能及时挽救，就意味着死亡。传统的止血药物有部分局限，新型的纳米药物还未走向市场。部分短肽快速止血的效果突出，但创伤界面互相作用而导致止血快速发生的机制依然是急需突破的难点。
关键词：创伤；快速止血；机制
中图分类号：R817.1
The Opportunities and Challenge for study of rapid emostasis
YUE yuanyuan1, GONG jianping2, XU xiaofan1, LI mengmeng1, LUO Zhongli1
1(1. The College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016,
China;2. The College of First Clinical Medicine, Chongqing Medical University, Chongqing 400016,
China)
Abstract: Trauma is always associated with blood bleeding and hemostatic process. If the normal hemostatic cascade mechanism do not work injured massive bleeding and, not any recue stop bleeding rapidly, it means high risky death. Traditional hemostatic medicines and materials have some limitations, and the new pre-Nan medicines are a potential to the market. Some peptides have a completive advantage to rapid hemostasis, but the mechanism of interaction where is due to stop bleeding processes between the nanomaterials and wound surface, is in urgent need of breakthrough.
Key words: Trauma; Rapid hemostasis; Mechanism;