自发及同步自发耳声发射特性研究
杭圣超1,2，彭诚1,2，李俊奎1,2，郭镇川1,2
基金项目：教育部博士点新教师基金（No.20100002120016）；自然科学基金青年基金（No. 81101114） 作者简介：杭圣超（1992-），男，硕士，生物医学信号处理 通信联系人：彭诚（1980-），女，助理研究员，从事生理信息检测等领域研究. E-（1. 清华大学深圳研究生院； 2. 清华大学医学院生物医学工程系）
摘要：随着耳机的普遍使用与环境中各种噪声的存在，听力损失已经成为影响人们生活的重大威胁之一。耳声发射能够客观的反应耳蜗功能状态，而自发耳声发射(Spontaneous otoacoustic emission，SOAE)和同步自发耳声发射（Synchronized spontaneous otoacoustic emission，SSOAE）对早期听力损伤更为敏感，两者之间的内在联系更有可能反应了耳蜗的内在特性，因而研究两者的相互联系，尤其是SSOAE向SOAE的变化过程，将有助于判断耳蜗的健康状况。本文采用实验室自行研制的耳声发射测量系统进行SOAE及SSOAE的测量和数据分析，对12位受试者进行了SOAE与SSOAE信号的检测和分析。实验结果表明，SSOAE中与SOAE频率对应的成分的幅度随时间呈现两种趋势——单调下降或者先升后降，反应了“耳声发射系统”从被Click声激励逐渐过渡到静息状态的内在特性。
关键词：生物医学工程；自发耳声发射；同步自发耳声发射
中图分类号：Q437
The study of the characteristic of SOAE and SSOAE
HANG Shengchao1,2, PENG Cheng1,2, LI Junkui1,2, GUO Zhenchuan1,2
(1. Graduate School at Shenzhen,Tsinghua University; 2. Department Biomedical Engineering,Tsinghua University)
Abstract: With the widespread use of headphones and the presence of various noise environments, 25 hearing loss has become one of the major threat affecting one of people's lives. Otoacoustic emission can reflect the functional status of cochlear, while the Spontaneous otoacoustic emission(SOAE) and the Synchronized spontaneous otoacoustic emission(SSOAE) signals are more sensitive for early stage hearing damage, the inner link of two signals is more likely to show the inherent property of cochlear. Therefore, studying the interrelation of them , especially the 30 transition process from SSOAE to SOAE, will be helpful to judge the health condition of cochlear.In this paper, SOAE and SSOAE of 12 subjects were measured and data analyzed based on an OAE measurement systems developed by the laboratory.The result indicates that the amplitude of those SSOAE signals that share the same frequency as in those SOAE signals had two kinds of temporal trends as the time passes: monotonically  decreasing or first increases then decreases, which reflected the inherent property of the “OAE system” transiting from the stimulation to the quiescent condition.
Key words: biomedical engineering; Spontaneous otoacoustic emission; Synchronized spontaneous otoacoustic emission